COVID-19 triggered remarkable changes in both the digital behaviour and the socio-cultural outlook of individuals and organizations. The Cybersecurity domain is a major beneficiary of these changes, which are projected to remain permanent. Notwithstanding the transformation, however, major adjustments are imminent to strengthen the existing protocols and make them suitable to address the emerging technological concepts, given that the existing cyber defence approaches have proved unreliable and insufficient. Chapter seven introduces post-pandemic Cybersecurity projections in artificial intelligence, big data, telemedicine, and aviation. It lays emphasis on the fascinating Cybersecurity research and innovations that will dominate the 2021 to 2025 window.